Chris Beardsley's Research
Chris is one of my favorites. I get his email information.
Dr Brad Schoenfeld's research supports Beardsley's; longer rest periods for hypertrophy.
However, one of the primary factors for hypertrophy, based on Shoenfeld's research is...
Metabolic Stress
This is what is commonly termed as, The Pump.
The Pump is created when arterial blood flow from the heart is pumped into the working muscles.
The muscle contraction in performing repetition in a set restricts ventricle blood flow back to the heart. The blood is trapped in the muscles being worked, pumping them up.
The Pump increases the production of lactate which trigger hypertrophy. Lactate accumulation is one a prime factors behind...
KAATSU/Occlusion Training
Practical Occlusion Training
Dr Jeremy Loenneke
Here is the downstream, domino effect...
"Lactic Acid > Acidic Environment > Growth Hormone Secretion"
The Reason for Short Rest Periods Between Hypertrophy Sets
1) With short rest periods between sets (about 60 seconds) there is less ventricle blood flows back to the heart.
2) With short rest period, The Pump is magnified; more blood remain in the muscles, less escapes.
3) The Pump is magnified to an even greater extent when a tourniquet is applied to your leg or arm with moderate tension; allowing a trickle of ventricle blood flow back to the heart.
Longer Rest Periods Between Hypertrophy Sets
Longer rest period between sets allow for more deflation of The Pump and less lactate accumulation.
Long rest periods work for increasing muscle mass; more effective at increasing strength compared to short rest periods.
However, based on research and anecdotal data, short rest period work, as well.
Summary
Long Rest Periods and Short Rest Periods elicit a somewhat different Hypertrophy Training Effect. Each has a benefit.
Kenny Croxdale