offwidth
Level 10 Valued Member
Half and even full marathons are really just entry level when it comes to serious locomotive endurance…HIIT and LISS trigger nearly identical adaptive responses. Both increase mitochondrial and capillary density, stroke volume, left ventricle hypertrophy, enzymatic profile etc.
LISS increases capillary density to a greater extent, HIIT improves qualitative aerobic glycolysis to a greater extent. These factors are probably the biggest difference between the two adaptive responses.
Both improve aerobic output of the same hardware using fats or carbs but they approach it from different signalling pathways.
HIIT can anchor or create modest cardio fitness and improve aerobic glycolysis in all but the best conditioned athletes. LISS operates with a considerably more distant horizon. One could almost certainly work up to a half marathon using only HIIT, but my guess is that would be about the limit (I did come across story of a man who did a full marathon using only HIIT- his time was somewhat poor and his feet hurt terribly, but he finished).
Compare that to the output of people who do 6-8hrs minimum LISS per week for whom a half marathon is not a challenge assuming their LISS is running. If they get their LISS biking, they might not do any better on a marathon than the HIIT trainee.